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Two new weight-loss drugs tested and trialled

Over in the US, two weight-loss drugs have been tested against one another to see which is most effective. Mounjaro was found to be more optimal than Wegovy.

Two new weight-loss drugs called Mounjaro and Wegovy have been tested and trialled against one another to see which is the most efficient.

In a study published in the New England Journal of Medicine, researchers said that both drugs lead to significant amounts of weight loss, but Mounjaro ultimately came out on top. The drug contributed to 20% weight reduction over 72 weeks compared to Wegovy’s 14% under the same conditions.

The study also stated that both options were viable for different medical scenarios and had a place on the healthcare market. Researchers concluded that Mounjaro was the preferred choice for those looking to lose the most weight.

In order to conduct the trial, 750 obese people were told to take the highest dose of either drug possible without causing harm. Both Mounjaro and Wegovy work by altering chemicals in the brain to trick the body into believing it is ‘full,’ though they have slight differences in function.

It’s worth noting that the trial was paid for by Eli Lilly, the manufacturer of the winning drug Mounjaro.

According to the published results, 32% of participants lost a quarter of their body weight on Mounjaro compared to 16% on Wegovy. Their waistlines also shrank by 18cm compared to 13cm on Wegovy. Mounjaro’s trialists also had better blood pressure, blood sugar and cholesterol levels. Interestingly, women tended to lose more weight than men.

Tons of research is currently underway in the weight-loss drug market. We’re sure you’ve likely seen comments and jokes about celebrities taking Ozempic, the highly-publicised drug that suppresses appetite by producing insulin.

It has become so synonymous with sudden weight loss that many people use the drug’s name as an adjective to describe a change in face shape or figure.

And while drugs to help support those looking to change their lifestyles and habits are undoubtedly a good thing, there is a growing sense that these type of solutions avoid the root cause of the problem.

Ultimately, we need to be healthier at the dietary level, with greater emphasis on exercise and balanced living.

Speaking to the BBC, Professor Naveed Sattar from the University of Glasgow said that while we are close to a possible method of ‘obesity prevention’ via weight loss drugs, ‘it would be far better to make our society healthier.’

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